Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in ...

Several seminal studies published in Gut have demonstrated a strong association between dysfunctional sucrase-isomaltase (SI) ...

Early broadly neutralising antibody responses against the E1E2 glycoprotein seem to be important for preventing persistence ...

Background Gastric cancer (GC) ranks among the most prevalent lethal tumours globally. Cancer-associated fibroblasts (CAFs) are pivotal in creating an immunosuppressive tumour microenvironment (TME) ...

5 Catholic Kwandong University College of Medicine Department of Medical Science, Gangneung-si, The Republic of Korea Background Dipeptidyl peptidase-4 inhibitors (DPP-4is) have been reported to ...

Background For large non-pedunculated rectal polyps, en bloc resection via endoscopic submucosal dissection (ESD) is typically recommended due to presumed higher risk of submucosal invasive cancer ...

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We read with great interest the article by Adams et al in *Gut* on the development and validation of the Admission Model for Intensification of Therapy in Acute Severe Colitis (ADMIT-ASC) score to ...

We thank Drs Fujisawa and Fujikawa for their thoughtful comments, which highlight professional and organisational determinants that complement our data on waste generation.1 2 In our multicentre study ...

BACKGROUND/AIMS Intestinal metaplasia (IM) is a common finding at the oesophagogastric junction, but the aetiopathogenesis of the different IM subtypes—that is, incomplete IM (specialised columnar ...

Background Patients with long-standing UC have an increased risk for the development of colonic neoplastic lesions. Chromoendoscopy (CE) has been proven to enhance neoplasia detection while the role ...

Background Small intestinal bacterial overgrowth (SIBO) is a clinical syndrome with abdominal complaints and malabsorption. Despite concerns over cure rates, recurrence, and antibiotic resistance, ...