If the 49ers win Sunday in Houston, they’ll match their overall win total from last season and they’ll be alone atop the NFC ...

San Francisco 49ers' team reporter Briana Jeannel named Head Coach Kyle Shanahan the heart and soul of the team. She also ...

Mac Jones has been a massive addition to the San Francisco 49ers this offseason. The team is 4-1 when he starts this season, ...

A week after the San Francisco 49ers improbably dominated the NFL's second-ranked offense, they'll be given a far less ...

The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

Christian McCaffrey’s record-breaking run faces its toughest test yet as the San Francisco 49ers running back battles the Houston Texans’ top-ranked defense.

San Francisco 49ers head coach Kyle Shanahan detailed the team's latest injury report, opened up about his pregame speeches, ...

San Francisco's been without its top wideout for the whole regular season. Here's what we know about his potential return.

Despite a 5-2 start and significant injuries to key players like Nick Bosa and Fred Warner, the San Francisco 49ers are ...