It's the Mac Jones show for the 49ers for at least one more week as Brock Purdy is out with a toe injury that's caused him to miss all but two contests this season. Jones is 4-1 as a starter in Purdy's absence. The 49ers will also be without receiver Ricky Pearsall once again as he battles a knee injury.

Kansas City Chiefs coach Andy Reid knows great quarterback play. Before becoming head coach of the Philadelphia Eagles in 1999, Reid was Brett Favre's quarterback coach in Green Bay. When Reid took over the Eagles, he drafted Donovan McNabb, who would become one of the NFL's best quarterbacks for a decade.