Siteman Cancer Center is deploying a mobile health van to 82 counties in Missouri and Illinois, offering cancer screenings, ...

MARION, Ill. (KFVS) - The Southern Illinois Made Expo is returning in 2025. The annual event is set for July 19 from 10 a.m.

ALTON - The Wedge and Southern Illinois University Edwardsville (SIUE) are proud to announce a groundbreaking partnership ...

If you played the Powerball last year, you might have the winning ticket in your pocket, however, you better turn it while ...

Brian Barone, who played two years for Marquette University, led SIU Edwardsville to its first NCAA Tournament berth.

The Illinois Department of Transportation stated they will be shutting down southbound I-57 between Exit 30 and Exit 45. This ...

Some residents of rural Illinois and Oregon are hoping to ditch their states and either join neighboring ones or create whole ...