A preclinical study uncovered a new gene therapy that targets pain centers in the brain while eliminating the risk of ...

A hidden immune stress switch may be driving chemotherapy nerve pain and scientists have found a way to turn it off.

Physical activity stimulates the release of endorphins (natural painkillers) and promotes the production of anti-inflammatory ...

For decades, opioids have been the blunt instrument of modern pain care, powerful enough to quiet severe suffering yet risky ...

SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain while protecting joint tissue. Instead of blocking pain ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

New research explores the link between distress and persistent pain in people with HIV and finds that inflammatory reactivity and hyperalgesia are not mediating factors. Distress is strongly ...

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

Pain isn't just a physical sensation-it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering. Researchers at the Salk Institute have ...

But Bongiorno wasn’t asking for drugs — she simply wanted help. For two years, Bongiorno, 54, had been living with pain that she describes as a deep burning sensation far worse than kidney stones or ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...