[3] The principle is that the lowest effective dose of an opioid should be used to minimize the impact of its effects. The first step in the ladder includes nonopioid analgesics, primarily ...

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Endo's slide into bankruptcy follows in the footsteps of Purdue Pharma – which filed in 2019 but is still negotiating opioid settlement and corporate restructuring terms – as well as ...

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Objectives were to provide dose-increment justification for conversion of a patient from conventional enteric-coated divalproex to a once-daily divalproex ER regimen and to discuss the ...

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