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Houston Texans, San Francisco 49ers

Texans vs. 49ers 2025 Prediction, Odds, Picks - Oct 26

The Houston Texans (2-4) are considered favorites (-1.5) according to the oddsmakers ahead of their game versus the San Francisco 49ers (5-2) on October 26, 2025, starting at 1 p.m. ET, airing on FOX.

USA TODAY Touchdown Wire on MSN · 4h

49ers vs. Texans picks: Who do experts predict will win Week 8 matchup?

Texans Wire · 12h

Houston Texans vs. San Francisco 49ers live stream, TV channel, start time, odds | Week 8 2025

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How to watch the 49ers vs. Texans on Sunday

Christian McCaffrey was named the NFC player of the week for his performance against Atlanta on Sunday Night Football, rushing for 129 yards and a pair of touchdowns, and adding 72 receiving yards.

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NFL prop bets Week 8 2025: Texans vs. 49ers

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Statistical Breakdown: How Texans and 49ers stack up before Week 8's showdown

49ers rule out Brock Purdy, Ricky Pearsall

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· 15h · on MSN

Texans vs. 49ers: Three key matchups that may decide Sunday's game

San Francisco's Christian McCaffrey and George Kittle pose challenges for Houston's defense, and 49ers' pass rush will be key.

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49ers rule out Brock Purdy, Ricky Pearsall for Texans game

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49ers Announce Brock Purdy Status Before Texans Game

5hon MSN

3 Critical Matchups to Watch When the 49ers Face the Texans

Don't let the 2-4 record of the Houston Texans fool you. That is a fairly strong team the San Francisco 49ers will be taking on in Week 8. Defeating them won't

Niners Wire

San Francisco 49ers vs. Houston Texans live stream, TV channel, start time, odds | Week 8 2025

Preview the San Francisco 49ers' NFL Week 8 matchup with the Texans, including live stream, TV channel, odds, and game information.

18hon MSN

Texans offer enticing matchup for 49ers' ailing defense: ‘You definitely see opportunities'

A week after the San Francisco 49ers improbably dominated the NFL's second-ranked offense, they'll be given a far less formidable test when they visit the Houston Texans.

1don MSN

With Nico Collins out vs. the 49ers, the Texans' effort to improve offense just got harder

The Houston Texans will be without Nico Collins for Sunday's game against the San Francisco 49ers. Jayden Higgins and Jaylin Noel must step up.

Texans receive unfortunate Nico Collins, Christian Kirk injury updates for 49ers game

The Houston Texans receive unfortunate injury updates for the San Francisco 49ers game regarding Nico Collins and Christian Kirk.

Brock Purdy Out for 49ers vs. Texans amid Turf Toe Injury, Mac Jones to Make 6th Start

San Francisco 49ers quarterback Brock Purdy has been ruled out for his team's Week 8 matchup against the Houston Texans amid his recovery from turf toe.

1don MSN

49ers' Kyle Shanahan has chance to flex greatness at Houston Texans

Ever since Kyle Shanahan took over as the head coach of the San Francisco 49ers, there has been a certain section of fans who have waited for the other shoe to drop.