The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

Our expert Week 8 NFL predictions expect the 49ers to cover the spread behind All-Pro running back Christian McCaffrey!

The 49ers are nearly halfway through the regular season, and their record is 5-2. And you are what your record says you are, ...

But, Albert Breer of Sports Illustrated highlighted why the 49ers might not be aggressive at this season's trade deadline ...

The San Francisco 49ers have a better record than the Houston Texans, but the oddsmakers have the Texans as favorites. They ...

San Francisco 49ers head coach Kyle Shanahan detailed the team's latest injury report, opened up about his pregame speeches, ...

San Francisco's been without its top wideout for the whole regular season. Here's what we know about his potential return.

Three years ago, San Francisco shocked the NFL by trading for Christian McCaffrey, arguably the game's best all-around ...

A new generation of general managers is more willing to take risks, and a later trade deadline allows teams to plan for the ...

The man who often tells you "don't be surprised" lists fantasy football players who have surprised him most this season.

Despite a 5-2 start and significant injuries to key players like Nick Bosa and Fred Warner, the San Francisco 49ers are ...