The San Francisco 49ers have not been healthy this season, and with Fred Warner and Nick Bosa out for the season, they will ...

Here's the latest on San Francisco 49ers star wide receiver Brandon Aiyuk following a knee injury last season.

Head coach Kyle Shanahan on Friday told reporters wide receiver Brandon Aiyuk is making progress toward a return that could ...

Aiyuk suffered a torn ACL and MCL in October 2024. Due to the injury occurring mid-season, the star receiver has yet to make ...

The 49ers could open wide receiver Brandon Aiyuk's 21-day practice window as soon as next week, coach Kyle Shanahan said ...

Those who were declared out Sunday were quarterback Brock Purdy (toe), center Jake Brendel (hamstring), edge rusher Bryce ...

Kyle Shanahan’s San Francisco 49ers lead the NFC West, even without one of Brock Purdy and Mac Jones’ key weapons on the ...

If the 49ers win Sunday in Houston, they’ll match their overall win total from last season and they’ll be alone atop the NFC ...

The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.