When we use androgen deprivation therapy, we are lowering testosterone levels typically by turning off the testes from making testosterone. This starves cancer cells, causing them to shut down, ...

External-beam radiotherapy (RT) is an established modality for definitive management of localized prostate cancer (LPCa). 1 Despite promising results with dose-escalated RT, a substantial proportion ...

A recent trial reveals metformin does not enhance survival in metastatic prostate cancer but offers significant metabolic ...

So when my urologist said in 2019 that my PSA test showed the most aggressive form of prostate cancer, I was not prepared. I was 68, and my annual tests had always been normal. Soon I embarked on a ...

Prostate cancer ranks high among male mortality causes worldwide. In this article, Sandy Srinivas, MD, discusses androgen deprivation therapy as a treatment for advanced prostate cancer and ...

Androgen deprivation therapy is commonly used to treat prostate cancer, often on an open-ended basis for therapy of advanced prostate cancer. It is estimated that 44 percent of men with prostate ...

Drs Sandhya Srinivas and Rana R. McKay discuss bone health and survivorship, including risk factors and potential side effects with androgen deprivation therapy in patients with prostate cancer.

Levine GN, D'Amico AV, Berger P, et al. Androgen-deprivation therapy in prostate cancer and cardiovascular risk: a science advisory from the American Heart Association, American Cancer Society, and ...

Patients with high-risk, locally advanced, or metastatic prostate cancer starting long-term androgen deprivation therapy are being recruited. The first comparative survival data were reported at ASCO.

Therapeutic Rationale Androgens can drive prostate cancer growth, thus providing the rationale for using deprivation of androgens as a first line of treatment for prostate cancer. Unfortunately ...