You could spend a whole day shopping and still not see all the treasures inside this Southern Illinois antique store.

Siteman Cancer Center is deploying a mobile health van to 82 counties in Missouri and Illinois, offering cancer screenings, ...

MARION, Ill. (KFVS) - The Southern Illinois Made Expo is returning in 2025. The annual event is set for July 19 from 10 a.m.

If you played the Powerball last year, you might have the winning ticket in your pocket, however, you better turn it while ...

In the last five years, voters in 33 Illinois counties have been asked if they want to consider separating from Chicago’s ...

Brian Barone, who played two years for Marquette University, led SIU Edwardsville to its first NCAA Tournament berth.

The Illinois Department of Transportation stated they will be shutting down southbound I-57 between Exit 30 and Exit 45. This ...

CARBONDALE — Illinois staged a dramatic comeback with a seven-run eighth inning to erase a late deficit and defeat Bellarmine ...

Despite scoring a season-high in points, t Illinois University women's basketball team (4-25 overall, 2-18 conference) ...

Southern Illinois aims to end its 4-game home slide with a victory against Illinois State. Saturday's meeting is the first of the season between the two teams.