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Ohio State vs Penn State prediction, pick, odds, spread

Ohio State vs. Penn State prediction, odds, time, line: 2025 College Football Week 10 picks

The No. 1 Ohio State Buckeyes (7-0) and the Penn State Nittany Lions (3-4) play on Saturday, November 1, 2025 at Ohio Stadium in a battle of Big Ten opponents.

· 2d · on MSN

Penn State vs Ohio State picks, predictions for college football Week 10 game Saturday

· 3d · on MSN

Updated betting odds, point spread ahead of Ohio State-Penn State football game

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Big Ten football: No. 23 USC visits Nebraska — and No. 1 Ohio State hosts slumping Penn State this weekend

Each of these teams has at least a remote chance of earning a College Football Playoff berth by avoiding any more regular-season losses.

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Tale of the tape: Ohio State offense vs. Penn State defense

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Live coverage of Penn State hockey at Ohio State Big Ten opener

14h

Joel Klatt previews matchup between Ohio State and Penn State

Ohio State's defense, with its No. 1 ranking, continues Saturday when the Buckeyes host a reeling Penn State on FOX's Big Noon Saturday, a game Joel Klatt says

1don MSN

How Ohio State’s Matt Patricia turned out to be the ‘home run’ hire Ryan Day — and his players — needed

There was a narrative hovering over Matt Patricia when he was hired by Ohio State football. His time with the Buckeyes has shut that down.

12don MSN

Former Ohio State coach Urban Meyer on Utah football 'my favorite two years I've ever had'

Hear what former Ohio State coach Urban Meyer said about his time coaching with Kyle Whittingham at Utah football.