Abstract The members of the team that discovered insulin sold the patent to the University of Toronto for $1 each because they felt that the drug belonged to the public. Nearly 100 years later, ...

Abstract A 61-year-old woman presented to the emergency department with chest pain. ST-segment elevations were revealed on ECG. A coronary angiogram showed normal coronary arteries, but left ...

There is sexism in medicine, but there may also be a more insidious obstacle. I’ve been haunted at every step of my career by the fear that I am a fraud. And not only do we women tend to perseverate ...

Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle ...

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

Methods In this phase 3, double-blind, placebo-controlled trial, we randomly assigned patients with unresectable EGFR -mutated stage III NSCLC without progression during or after chemoradiotherapy to ...

Data are lacking on the proportion of physicians who face malpractice claims in a year, the size of those claims, and the cumulative career malpractice risk according to specialty. We analyzed ...

Methods We randomly assigned patients with type 2 diabetes and chronic kidney disease (defined by an estimated glomerular filtration rate [eGFR] of 50 to 75 ml per minute per 1.73 m 2 of body-surface ...