We do not know if other non-medicinal treatments and innovative healthcare support helped to reduce the number of seizures or improve children's quality of life because the evidence was limited and ...

The effect of oral riboflavin (vitamin B 2) supplements on blood pressure is uncertain. Large, well-conducted trials are needed to assess the effect of riboflavin on blood pressure lowering.

Due to a lack of robust evidence, the benefits and risks of adding chemotherapy directly into the abdominal cavity (intraperitoneal chemotherapy, or IPC) for stomach cancer are unclear.

We do not know if medicinal and non-medicinal treatments help reduce impulsive-compulsive behaviors in people with Parkinson's disease because the currently available evidence is limited and uncertain ...

• Blood pressure-lowering medications lower the chance of death and probably reduce heart attacks and strokes in people with hypertension (high blood pressure) 60 years of age or older. • There may be ...

Simple hysterectomy may result in little to no difference in the number of deaths from any cause, life expectancy after treatment, deaths from cancer, cancer-free period after treatment, or the rate ...

Doctors need reliable ways to predict seizure risk after a first unprovoked seizure, to help guide diagnosis and treatment. This is especially important because a diagnosis of epilepsy can now be made ...

Our Handbooks describe the process of preparing and maintaining diverse types of systematic reviews. Handbooks are updated regularly to reflect advances in systematic review methods and in response to ...

Through our global network of Cochrane Groups, we harness a wide variety of specialist interests, skills and knowledge that help us create high quality, relevant health evidence. Our Thematic Groups ...

Plain language summaries are summaries of the health evidence that Cochrane produces, written in a way that everyone can understand. At Cochrane, we write systematic reviews of research into human ...

Cochrane has been improving people's lives and global health for more than 30 years. Our unique network of researchers, health professionals, patients and dedicated individuals has improved healthcare ...

Cochrane was established in 1993 in Oxford, UK, 'to facilitate the preparation of systematic reviews of randomized controlled trials of health care.' The Cochrane Centre, as we were then known, ...