An important flaw in the funding approach used by Canada’s public drug plans is highlighted by the findings of 2 articles related to the clinical value of direct oral anticoagulants (DOACs), published ...

KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department. [1] [1] It is a clinical spectrum ...

Nonalcoholic fatty liver disease refers to a spectrum of diseases from hepatic steatosis to NASH, a condition where fat accumulation causes inflammation and hepatocyte injury leading to cirrhosis. [1] ...

We do a very poor job of health workforce planning in Canada, in large part because of inadequate health workforce data. Inadequate health workforce data have economic costs because poor data limit ...

In its 2015 Quality of Death Index report, the Economist Intelligence Unit ranked Canada 11th in overall quality of death and 18th in availability of palliative care services.1 For efforts to develop ...

Since late 2023, new outbreaks have been reported in Bolivia, Brazil, Peru, and Cuba, including among travellers returning to Canada and the United States. [1] [1], [2] [2] Malaria, Zika, dengue, and ...

Iron deficiency and iron deficiency anemia are common during pregnancy and are associated with adverse outcomes Prenatal iron deficiency occurs in more than 30% of pregnancies in Canada. 1 It has been ...

Adenomyosis can affect any reproductive-aged woman, with incidence and severity increasing with age Historically thought to affect only older women, adenomyosis is now identifiable on imaging in 30% ...

Background: Fragility fractures are a major health concern for older adults and can result in disability, admission to hospital and long-term care, and reduced quality of life. This Canadian Task ...

Bupropion abuse is a growing public health problem Although bupropion shares some structural and pharmacologic properties with amphetamine, early research suggested the drug did not produce any ...

Major hemorrhage is a challenging clinical problem that can occur with traumatic injury, postpartum hemorrhage, major surgery and gastrointestinal bleeding. A massive hemorrhage protocol (MHP) should ...

Background: Children with major trauma have better outcomes when treated in pediatric trauma centres, but population-based data on access to these centres in Canada are lacking. We aimed to estimate ...