Original Article Published: 24 July 2002 Viruses as gene delivery vectors: Application to gene function, target validation, and assay development Michael T Lotze & Thomas A Kost Cancer Gene ...

Lentiviral vectors delivered by stereotaxic injection into the brain have been used to express miRNA-inhibiting sponges to study miRNA function in neurons in vivo 12.

Based on these results, similar translationally enhanced vectors were also developed using unstable GFP3 variants, which retain their short-half life characteristics in L. monocytogenes and therefore ...