Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ. These new blood cells are formed in the bone ...

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, has published new research in Science Advances detailing the company's CRISPR-based Cellgorithm technology, ...

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this ...

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimislecel ...

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through ...

Researchers have developed a method to confidently produce blood cell precursors from stem cells in mice, by activating a set of seven key genes in the laboratory. The team takes a step forward ...

Cellular redox status plays critical roles in cell division and differentiation, but the underlying mechanism is unclear. Here we explored the effect of redox status on stem cell identity in distal ...