The San Francisco 49ers could look to shed some ... ClutchPoints' Enzo Flojo named the Buffalo Bills. "The Buffalo Bills have been on the brink of a Super Bowl appearance for years," wrote Flojo.

he could be a strong fit with the Bills in a hybrid role. San Francisco 49ers wide receiver Deebo Samuel Sr. / Sergio Estrada-Imagn Images Many were excited to see Curtis Samuel coming to Buffalo ...

San Francisco 49ers (5-6) 4th NFC West @ Buffalo Bills (9-2) 1st AFC East Kickoff: 8:20 p.m. EST, Sunday, December 1st Location: Highmark Stadium, Buffalo, New York ...

Buffalo Bills and San Francisco 49ers reveal game-day inactives as both teams prepare for winter wonderland matchup at Highmark Stadium. The Buffalo Bills (9-2) prepare for a critical Week 13 ...

The Baltimore Ravens head to Orchard Park, New York for a much anticipated matchup with the Buffalo Bills, with the winner ... their home game against the San Francisco 49ers in Orchard Park ...

The Buffalo Bills are set to have a classic snow game matchup against the San Francisco 49ers in Orchard Park. The Buffalo Bills will look to build on their six-game win streak when they host the ...