Obesity polygenic risk scores (PRS) explain substantial variation in body mass index (BMI), yet associations between PRSs and appetitive traits in children remain unclear. To better understand ...
PRSs have typically been derived using European ancestry genome-wide association study (GWAS) data, resulting in substantially lower predictive power when applied to non-European samples, in ...
Polygenic risk scores for IOP and VCDR significantly enhance glaucoma risk prediction, especially for primary open-angle glaucoma. The study utilized data from multiple cohorts, including the Canadian ...
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