In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

In an era where the U.S. healthcare system spends $4.5T annually yet faces systemic failures, with life expectancy plummeting to a three-decade low and chronic disease rates at an all-time high, the ...

The artificial cell nucleus (right) constructed using the purified DNA was morphologically very similar to the natural cell nucleus derived from an egg (left). A team led by Professor Kazuo Yamagata ...

Weill Cornell Medicine researchers have found that temporarily disabling a protein complex that organizes DNA into loops ...

A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital role in safeguarding the most vulnerable areas of DNA. By forming ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...