The endosomal sorting complex required for transport (ESCRT) machinery is an evolutionarily conserved multisubunit protein complex that remodels cellular membranes. Beyond its classical role in ...

Transmembrane protein 53 (TMEM53) is an outer nuclear membrane protein that plays a crucial role in maintaining skeletal homeostasis. Pathogenic variants in TMEM53 have been identified as the genetic ...

Researchers discover that Alzheimer's-linked APP protein protects neurons by clearing toxic leaked nuclear waste via ...

Researchers at Niigata University's Brain Research Institute have uncovered a new function of amyloid precursor protein (APP) ...