Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of ...

Among modern cancer therapies, immune checkpoint inhibitors (ICI) are among the most successful treatment methods. These antibodies activate the immune system and enable T cells to detect and destroy ...

A team led by USC Stem Cell scientist Zhongwei Li, PhD, has produced some of the most complex and mature lab-grown kidney models to date. Supported by a three-year grant from the California Institute ...

aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

Emerging evidence demonstrates the important role of ferroptosis, a novel regulated cell death, in the initiation and progression of acute kidney injury (AKI). However, the activation mechanism of ...

Acute kidney injury (AKI) is a common clinical disease with complex pathophysiological processes and with high morbidity and mortality. Severe mitochondrial damages, such as mitochondrial swelling and ...

With a so-called cryo plasma-FIB (Plasma Focused Ion Beam) scanning electron microscope with nanomanipulator, Goethe University in Frankfurt (Germany) is expanding its research infrastructure with a ...

This is the longest-lived set of developing kidney organoids derived from tissue stem cells The kidney developed over a half a year, enabling real-time observation, gene isolation for birth defects ...

HLA sensitization poses a major challenge to kidney transplantation for patients with end-stage kidney disease, especially for highly sensitized candidates. Attempts at antibody elimination ...