RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

RNA sequencing is a powerful tool that helps researchers uncover novel biological insights into the transcriptome. This free eBook allows readers to learn about RNA sequencing (RNA-Seq) by explaining ...

Eight years ago, 10x Genomics launched the first commercially available single-cell RNA sequencing (scRNA-seq) product for the company’s flagship instrument, the 10x Chromium. (This occurred one year ...

An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the sequences ...

UC Vice President for Research Patrick Limbach is a key figure in the National Academies’ massive undertaking to sequence RNA in the next 15 years. A chemist who leads the University of Cincinnati’s ...

In a recent study published in the journal Nature Methods, a group of researchers developed a novel method called Ribonucleic Acid (RNA) High-Order Folding Prediction Plus (RhoFold+). This deep ...

Now, a pair of Scripps Research Institute scientists has taken a significant step toward answering that question. The scientists have synthesized for the first time RNA enzymes that can replicate ...