Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...

To test the efficacy of the patch, the team loaded the EW-MNs with rivastigmine (a drug commonly used to treat Alzheimer's and Parkinson's disease). In animal studies using guinea pigs, the ...

Surface plasmon resonance (SPR) detectors monitor molecular interactions without labels and in real time. SPR imaging (SPRi) has the additional advantage of increased throughput since it monitors ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vivtex Corporation, a pre-clinical biotechnology company focused on the oral delivery of biologics into systemic blood circulation or localized into GI tissue, ...

Monash University and Seaport Therapeutics have developed a new approach to delivering drug molecules that piggybacks onto natural fat absorption pathways to allow oral delivery of some drugs ...

The demand for novel medications is escalating due to the diminishing efficacy of long-standing antibiotics. Chemists and pharmaceutical researchers are vigorously pursuing innovative compounds, ...

In this interview, News Medical talks to Patrick D. Sinko about the role of particle size, dose, and confinement parameters in advancing drug absorption modeling. Could you explain what a boundary ...

Stone wool fiber dissolution in physiological environments is a key process underlying their long-term behavior and safety, yet robust and reproducible in vitro ...

The European Medicines Agency (EMA) has published a guideline on evaluating drug interactions in the gastrointestinal tract that addresses situations in which extrinsic factors in the gastrointestinal ...

Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematized review revealed critical gaps in methodology. Of 18 original research articles selected ...

As discussed in Chapter 2, there are potential advantages for the use of topical medications to treat pain indications, including provision of local, regional, and systemic therapeutic effects, as ...