First reported in 1928 by Otto Diels and Kurt Alder, the Diels-Alder reaction is one of the most relevant transformations in organic chemistry. Its capacity to generate six-membered rings enables the ...

It's natural for chemists to wonder whether the ingenious reactions that have been invented in the laboratory over the past century were actually harnessed millions of years ago by enzymes, nature's ...

The Diels-Alder reaction is widely used in organic synthesis. Chemists appreciate its simplicity, reliability, and the ability to influence its course and change the conditions of the process. Several ...

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The properties of organic molecules are intimately related to their shape. In many structurally complex organic molecules, shape is influenced—or dictated—by the three-dimensional orientation of ...