New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, ...

A team of researchers has developed a method that could transform the field of protein engineering. The new approach, called AI-informed Constraints for protein Engineering (AiCE), enables rapid and ...

Tel Aviv-based AI-enabled computational protein engineering platform Scala Biodesign announced its launch today with $5.5 million in seed funding. The round was led by TLV Partners, an Israeli venture ...

Nanopores (otherwise known as transmembrane β-barrel pores (TMBs)) are perhaps best known for their role in the sequencing of nucleic acids—both DNA and RNA. They can also be used to sequence peptides ...

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), ...

Inside the race to turn one of cell biology’s least understood processes into a new foundation for drug development and ...

Enzymes in laundry detergents, insulin for diabetes, and the antibodies and enzymes used in medicine: all of these exist thanks to protein science and engineering. Protein engineering has transformed ...

Computational Chemistry is the study of complex chemical problems using a combination of computer simulations, chemistry theory and information science. Also called cheminformatics, this field enables ...