A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...

New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...

Every multicellular organism, from tiny worms to humans, elephants, and whales, needs a way for their cells to connect with ...

Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

Researchers have created nanoparticles that can remove disease-driving proteins while also delivering a chemotherapeutic or ...

A new approach engineers immune cells to recognize byproducts of cancer cells to trigger migration toward the tumor.