Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process ...

Researchers analyze 2.2 million genomes to show that addiction risk is primarily driven by broad genes affecting brain wiring and impulse control, not drug-specific traits.

A new study reveals how the brain triggers the breakdown of stable fat cells that normally resist diet and exercise. This ...

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well ...

Inflammation and mitochondrial function as mechanisms in accelerated aging (AA) across substance use disorders (SUDs). This figure presents a proposed model linking genes associated with ...

Depression is a mental health condition that affects 280 million people worldwide. It is twice as common in women than men and this pattern starts to develop during adolescence. Researchers have ...

Don’t get old before your time. A number of very common everyday habits can accelerate biological aging, putting extra stress on your cells and organs and making yourself more susceptible to certain ...