Auto-antibodies erroneously target their own proteins and enzymes. When these auto-antibodies target type 1 interferons, they can neutralize their function as signal proteins for the immune system.
5d
NMR reveals site-specific structural signatures of therapeutic antibodies without isotope labeling
Monoclonal antibodies are widely used to treat diseases ranging from cancer to autoimmune disorders. The safety and efficacy of these biologic drugs depend on maintaining their correct ...
Autoantibodies are antibodies that target the body’s own antigens. These antigens may consist of proteins, nucleic acids, carbohydrates, or lipids expressed ubiquitously throughout the body or only in ...
Recently, scientists found that some people who suffered from COVID-19 had auto-antibodies targeting their own type 1 interferons, which are important immune signaling proteins. Now, researchers ...
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