Since the discovery that actin and actin-related proteins (ARPs) reside in the nucleus as integral subunits of chromatin-modifying and chromatin-remodeling complexes, efforts to uncover their roles in ...

Transcription of DNA into RNA is an extraordinarily complex, highly regulated process. Gene transcription depends on a complex molecular machine consisting of more than 100 proteins. It is turned on ...

Over the last several years the identification and functional characterization of the motor proteins actin and myosin in the nucleus has initiated a change in the view of nuclear processes. It is now ...

Actin, a protein with a well-known job in the cytoplasm and an active role in muscle contraction, moonlights in the nucleus. It's function there was not understood, but now scientists find that it ...

Cofilin is the major mediator of actin filament turnover in vivo. However, the molecular mechanism of cofilin recruitment to actin networks during dynamic actin-mediated processes in living cells and ...

A tiny chemical modification on one of the most abundant and important proteins in cells, actin, has long been somewhat mysterious, its function not fully understood, but scientists have now taken a ...

This is a preview. Log in through your library . Abstract A vast array of actin binding proteins (ABPs), together with intracellular signaling molecules, modulates the spatiotemporal distribution of ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

Aberystwyth UK – April 5 th 2023 – A new clinical study of adults with moderate joint health issues demonstrated that a novel iminosugar-containing dietary supplement ingredient, marketed as Q-actin® ...