But as always, the 49ers are significantly stronger whenever Christian McCaffrey is on the field. Against the Giants, he set multiple new records, with one achievement joining him to an exclusive club and placing him among a very select group of players to represent San Francisco.

NFL.com says teams are calling on Jauan Jennings, but with Aiyuk still ramping up and Shanahan signaling stability, a 49ers trade is unlikely.

The New York Giants play host to the San Francisco 49ers on Sunday in a battle of teams missing multiple star players on both sides of the ball.

In the late third and early fourth quarter and the Giants within 20-10, quarterback Mac Jones hit Kendrick Bourne for a 13-yard gain and then Shanahan proceeded to run the ball down New York’s throat with eight straight runs. McCaffrey got the first five and Robinson the last three, including an 18-yard touchdown run for a 27-10 lead.

Head coach Kyle Shanahan admitted that quarterback Brock Purdy is not close to returning from his toe injury.

Josh Dubow of the Associated Press also shed light on perhaps the most troubling Jennings stat this season, as 49ers QBs have just a 38.0 passer rating when targeting him, an extremely low rate made even worse by the interceptions that have occurred when Brock Purdy or Mac Jones have targeted him this year.

The San Francisco 49ers have reportedly shown interest in a big-time trade ahead of the Tuesday NFL trade deadline.

Preview the Week 9 matchup between the San Francisco 49ers and New York Giants with predictions, odds, over/under, spread, betting lines and more.