When the NFL season began, few would have bet the Cardinals (7-9) would enter Week 18 of the season with a better record than the 49ers (6-10). Expected to be the top seed in the NFC playoffs ...

The Arizona Cardinals have one final game left this season, closing it out at home against the San Francisco 49ers. Kickoff from State Farm Stadium is at 4:25 p.m. ET (2:25 p.m. Arizona time ...

Samuel has been a versatile piece for the 49ers since his arrival in 2019 as a second-round pick. In 81 games for San Francisco, he's tallied 5,935 scrimmage yards and has been a pivotal for the 49ers ...

For coach Jonathan Gannon and QB Kyler Murray, ending the season with a win will give Arizona a confidence boost heading into the offseason.

Here are three reasons why the 49ers will beat the Cardinals. The 49ers will have some trouble getting as motivated against the Cardinals as they were against the Lions. One game was against an ...

The 49ers granted Samuel and his agent permission to seek a trade once this latest request came a month ago, when Samuel, 29, ...

D.J. Reed's path to free agency started with the San Francisco 49ers, who drafted him in the fifth round of the 2018 NFL ...

The San Francisco 49ers are preparing for their Week 18 contest against the Arizona Cardinals on Sunday at State Farm Stadium in Glendale, Arizona. Several key players were absent from the second ...

Discussing the 49ers preparations for their 2024 season finale against the Arizona Cardinals, including quarterback changes, players to watch and the importance of finishing the season strong with ...

How do all 32 teams in the NFL stack up against each other going into the 2025 NFL offseason? Here's breaking down who's ...

Following a narrow 40-34 home loss to the Detroit Lions on "Monday Night Football," the 6-10 49ers conclude the season against the 7-9 Arizona Cardinals on Sunday at State Farm Stadium.

TV: FOX. Radio: 98.7 FM. Last time they played: The 49ers made easy work of the Cardinals in a 45-29 win last December. That defeat is the most points the Cardinals have allowed in a game since 2016.