Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a typical 2-4 losing team. They boast o

The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the Rams. A big reason is the play of Jones under center. The veteran has resurrected his career in leading San Francisco forward despite injuries to a laundry list of players including Brock Purdy, Brandon Aiyuk, and Nick Bosa.

The Houston Texans look to right the offense on Sunday when they battle the San Francisco 49ers and they'll be doing so short-handed on offense.

Those who were declared out Sunday were quarterback Brock Purdy (toe), center Jake Brendel (hamstring), edge rusher Bryce Huff (hamstring), wide receiver Ricky Pearsall Jr. (knee) and defensive lineman Yetur Gross-Matos (knee). Lenoir was questionable along with linebacker Luke Gifford (hamstring) as was guard/tackle Spencer Burford (knee).

The Houston Texans will be without Nico Collins for Sunday's game against the San Francisco 49ers. Jayden Higgins and Jaylin Noel must step up.

Ever since Kyle Shanahan took over as the head coach of the San Francisco 49ers, there has been a certain section of fans who have waited for the other shoe to drop.

Matt Maiocco identifies five 49ers players to watch in San Francisco's Week 8 game against the Houston Texans.