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Powerball winning numbers for Wed., Oct. 22, 2025

· 5h · on MSN

Winning Powerball numbers for Wednesday, Oct. 22: See how many Ohioans won prizes

A lthough no one won the $321 million Powerball jackpot in the latest drawing on Wednesday, Oct. 22, many players in Ohio took home a bit more cash. The winning numbers for Powerball on Wednesday were 18, 37, 52, 54 and 60. The Powerball was 12 and the Power Play was 2x.

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Powerball winning numbers for Wednesday, Oct. 22, 2025; jackpot $320 million

· 5h · on MSN

Winning Powerball numbers for the $320 million jackpot on October 22, 2025: See all the prizes hit in Ohio

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See list of biggest jackpots in Powerball, Mega Millions history, Ohio wins

The biggest Powerball win in Ohio came in June 2010, when an anonymous winner claimed the $261.6 million jackpot through a ...

Amid school funding concerns, where are lottery profits?

With school funding concerns and high property taxes, viewers asked NBC4 to look into Ohio Lottery payments for schools.

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