The penultimate matchup of the First Four belongs to No. 16 teams Mount St. Mary’s and American University. Both teams finished the season with 22-12 records and earned 16 seeds, warranting a play-in game to make the first round and official 64-team bracket.

This NCAA basketball bonanza kicks off with the First Four Round – four games in each tournament to determine the final four teams in the Round of 64. It’s the last puzzle piece before the March Madness bracket is complete.