The 49ers have an injury issue that previously wasn't known. Nick Wagoner of ESPN.com reports safety Malik Mustapha underwent an ACL repair following the 2024 season. He suffered the injury in Week 18,

San Francisco 49ers safety Malik Mustapha re-injured a torn ligament in his right knee last season and could miss the start of the 2025 campaign.

San Francisco 49ers safety Malik Mustapha is not expected to be available at the start of the 2025 season due to a torn ACL, according to ESPN's Adam Schefter. Mustapha suffered the injury after he was cleated in the knee during the second quarter of the 49ers' 47-24 loss to the Arizona Cardinals in Week 18 of the 2024 season.