With Manchester United taking on Arsenal on Matchday 1 of the 2025-26 Premier League, many are wondering why Andre Onana, Rasmus Hojlund, and Alejandro Garnacho are nowhere to be seen.

Kickoff from Old Trafford in Manchester is set for 11:30 a.m. ET. The Gunners are -118 favorites (risk $118 to win $100) on the 90-minute money line in the latest Manchester United vs. Arsenal odds, while Man United are +310 underdogs.

Preview the matchup between Chelsea FC and Crystal Palace with predictions, odds, over/under, betting lines and more.

Manchester United hosts Arsenal at Old Trafford in both clubs' 2025-26 English Premier League opener. Here is how to watch the game.

Season Opens Tomorrow, Friday, Aug. 15, as Defending Champions Liverpool Host Bournemouth at 3 p.m. ET on USA Network and Universo; Manchester United Host Arsenal This Sunday, Aug. 17 at 11:30 a.m. ET on NBC,

Preview the matchup between Arsenal FC and Manchester United with predictions, odds, over/under, betting lines and more.

Cole Palmer has expressed his excitement as Chelsea begin their 2025/26 campaign against Crystal Palace on August 17.

The schedule makers didn't do Ruben Amorim any favors to start the Premier League season, but his Manchester United showed up to play against Arsenal on Sunday.